Titlebook: Mechanisms of Secondary Brain Damage from Trauma and Ischemia; Recent Advances of o A. Baethmann,J. Eriskat,N. Plesnila Conference proceedi

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The natural course of lesion development in brain ischemial as in patients presenting with hemispheric stroke, considerable lesion growth was observed. In focal cerebral ischemia, lesions predominantly enlarge early (<12 hrs postinsult) and show complete ischemic injury due to pan necrosis in the vast majority of affected tissue. In global cerebral ischemi

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The role of inflammatory processes in the pathophysiology and treatment of brain and spinal cord trafollowed by the infiltration and accumulation of polymorphonuclear leukocytes (PMNLs). The role of the inflammatory cascade on traumatic outcome remains controversial. Pleiotropic cytokines appear to function both protectively and destructively. The induction of cytokines can lead to the expression

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Recovery from spinal cord injury — underlying mechanisms and efficacy of rehabilitation flaccid muscle tone is associated with a low persistence of F-waves and loss of flexor reflexes while H-reflexes are well elicitable. When clinical signs of spasticity become established, the electrophysiological parameters show little change. The divergent course of clinical signs of spasticity in

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Lessons from epidemiologic studies in clinical trials of traumatic brain injuryarmacological agents in traumatic brain injury. A great number (> 10,000) of patients has been prospectively analyzed forming an integrated database for further purposes. The development of these databases is based on earlier work by the European Neurosurgeons Jennett and Braakmann and the US-Trauma

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The MRC CRASH trial — a large, simple randomised trial of steroids in head injuryersus placebo in mild, moderate and severe head injury. Patients are eligible up to 8 hours from injury. To date the CRASH trial has recruited 9000 patients. The trial is recruiting from 200 hospitals in 50 countries with another 100 centres planning to join the trial. The target for recruitment is

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uses, there was no developed industry.. European interest in the possibility of exploiting Mesopotamian oil commercially had been manifested since the last quarter of the nineteenth century. Individuals and expeditions visited the area, and even before the turn of the century numerous reports had b