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Titlebook: Mechanisms of Oncogenesis; An update on Tumorig Domenico Coppola Book 2010 Springer Science+Business Media B.V. 2010 Chromosom.Oncology.car

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Carcinogenetic Pathway of Malignant Melanoma,that currently lacks effective treatment. The biology of melanoma is complex, with numerous different histologic subtypes, genetic predispositions, environmental factors, and clinical features though to play a role in carcinogenesis and outcome. The purpose of this chapter is to review the most rece
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Molecular Mechanisms of Central Nervous System Metastasis,y and mortality remain high. The mechanisms that impact metastases to the CNS remain unclear. The migratory and invasive properties of the individual primary tumor are directly related to its metastatic potential and malignant cells must manifest these properties in order to attain a more aggressive
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,Postmenopausal Hormone Replacement Therapy and Breast Cancer – Clinicopathologic Associations and Me of breast cancer is currently unknown, several molecular pathways have been identified to play a role in breast cancer development and progression. Perhaps the most important pathway involves the estrogen receptor (ER). More than two thirds of breast cancers show ER expression at the time of diagn
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Carcinogenesis of Lung Cancer,ncrease the risk of lung cancer, in particular adenocarcinoma. Adenocarcinoma of the lung is a stepwise accumulation of genetic abnormalities with morphological differences seen in the cytology and histology of atypical alveolar hyperplasia, bronchioloalveolar carcinoma and invasive adenocarcinoma.
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Genesis of Pancreatic Ductal Neoplasia,and targeted therapeutic options, which can be obtained through a better understanding of the cellular and molecular processes which lead to the development of pancreatic carcinoma, are key to improving the outcome of this highly lethal disease. The progress which has been achieved the last two deca
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Mechanisms of Carcinogenesis in Colorectal Cancer, pathways have been thought to play critical role in colorectal carcinogenesis, one of which is the chromosomal instability cascade, which is characterized by allelic losses on chromosome 5q ., 17p ., and 18q ., and the other is a pathway that involves microsatellite instability, which is regulated
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