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Titlebook: Mechanisms of Gene Regulation; Carsten Carlberg,Ferdinand Molnár Textbook 20141st edition Springer Science+Business Media Dordrecht 2014 c

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书目名称Mechanisms of Gene Regulation
编辑Carsten Carlberg,Ferdinand Molnár
视频video
概述Figure-driven textbook, i.e. ratio of text to figures is low.Expertly written textbook on a modern field of general interest, based on 10 years experience of teaching the course for which the textbook
图书封面Titlebook: Mechanisms of Gene Regulation;  Carsten Carlberg,Ferdinand Molnár Textbook 20141st edition Springer Science+Business Media Dordrecht 2014 c
描述.This textbook aims to describe .the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading from students of all the biomedical sciences in order to be better prepared for their specialized disciplines..A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is t
出版日期Textbook 20141st edition
关键词chromatin; gene regulation; protein structure; signal transduction; transcription factors; gene expressio
版次1
doihttps://doi.org/10.1007/978-94-007-7905-1
isbn_ebook978-94-007-7905-1
copyrightSpringer Science+Business Media Dordrecht 2014
The information of publication is updating

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Carsten Carlberg,Ferdinand Molnár gene expression is Ca2+/calmodulm dependent. We also demonstrate that hypoxia activates the extracellular-regulated kinase (ERK) and p38, but not JNK. Further, phosphorylation of ERK is essential for c-fos activation via SRE cis-element. Further characterization of nuclear signalling pathways provi
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Carsten Carlberg,Ferdinand Molnár strain distribution pattern (SDP). The SDP for hypoxic . is consistent with the hypothesis that parental strain differences are regulated by two genes. Cosegregation analysis suggest that the genetic control of . during hypoxia differs from the genes which control differential baseline .. Although
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Carsten Carlberg,Ferdinand Molnár gene expression is Ca2+/calmodulm dependent. We also demonstrate that hypoxia activates the extracellular-regulated kinase (ERK) and p38, but not JNK. Further, phosphorylation of ERK is essential for c-fos activation via SRE cis-element. Further characterization of nuclear signalling pathways provi
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