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Titlebook: Mechanisms of Cell-Mediated Cytotoxicity II; Pierre Henkart,Eric Martz Book 1985 The Editor(s) (if applicable) and The Author(s), under ex

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楼主: STH
发表于 2025-3-23 12:08:28 | 显示全部楼层
Both NK Sensitive and Resistant Mycoplasma Free Cell Lines Stimulate Release of NKCFof cytotoxic supernatants by murine or rat spleen cells. It was found that both NK sensitive and resistant mycoplasma free cell lines could stimulate release of NKCF. Some mycoplasma infected cell lines could generate cytotoxic supernatants, however, it is not clear whether the lytic activity is due to NKCF or some other agent.
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An Investigation of the Role of Soluble Cytotoxic Factors and Reactive Oxygen Intermediates in Lysis target cells (Roder et al., 1982), and the inhibition of lysis by superoxide dismutase (SOD; Roder et al., 1982), or hydroxyl radical (OH.) scavengers (Suthanthiran et al., 1984). Whether the ROI directly inflicted damage on the target cells, as is the case in some macro phage/neutrophil cytocidal systems (Nathan et al., 1979a; b), was unclear.
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Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/m/image/628704.jpg
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https://doi.org/10.1007/978-1-4684-8326-0T cell; antibody; antigen; bacteria; cell biology; cytotoxicity; immune system; immunity; immunology; lymphoc
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978-1-4684-8328-4The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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The Role of Cytoplasmic Granules in Cytotoxicity by Large Granular Lymphocytes and Cytotoxic T Lymphg experiments of markers released from red cell ghosts attacked by complement and by LGL in ADCC (3). Similar pore-like structures were reported to be associated with cytotoxicity by a cloned cell line with NK activity (4).
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Human NK Resistant Tumor Cell Lysis is Effected by IL-2 Activated Killer Cellsand polyspecificity that has not been found reproducible in any other anti-tumor lytic system, and therefore provides yet another interesting and potentially biologically relevant system in which to examine the mechanism of cell mediated cytotoxicity. This report addresses some of the basic aspects
发表于 2025-3-25 01:14:27 | 显示全部楼层
Biochemical Characterization of Natural Killer Cytotoxic Factorsimulate release of the factors (8), thus accounting for the dual effects of interferon on NK CMC (9). NKCF lyse only NK sensitive targets (2,4) and YAC-1 variants selected for resistance to NKCF are also resistant to NK CMC (10).
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