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Titlebook: Mechanisms in B-Cell Neoplasia; Workshop at the Nati Fritz Melchers,Michael Potter (Chief) Conference proceedings 1986 The Editor(s) (if ap

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Induction of Hematopoietic Tumors Using a Viral Construct Containing c-, cDNA from Normal Mouse SpleLB/c mice (reviewed in Potter, 1986) and murine T cell lymphomas induced by AKR and Moloney murine leukemia viruses (MuLV) (Steffen 1984, Selden et al. 1984, Li et al. 1 984, Corcoran et al. 1984). Studies on the c-. expression in plasmacytomas suggest that . can be deregulated by a variety of mecha
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Mammalian Cell Transformation by a Recombinant Murine Retrovirus Containing the Avian Erythroblastosforms immature avian erythroid and fibroblastic cells in vitro (Graf and Beug, 1978). The genome of AEV contains two distinct oncogenes, v-. and v-. (Vennstrttm and Bishop, 1982). V-. is a member of the . family of retroviral oncogenes (Yamamoto .., 1983). The products of these ..related oncogenes a
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Alpha-type B Cell Growth Factor and Complement Component C3: Their Possible Structural Relationship; Melchers .., 1985). In its activity as a synergistic growth factor, it therefore replaces a-type B cell growth factors (BCGF; Corbel and Melchers, 1984) which have been found to act at the same temporal point (restriction point) in the cell cycle (Melchers and Lernhardt, 1985). Furthermore, solubl
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A Growth-Factor Dependent B-Cell Hybridomaduce a microenvironment that will support the growth of transplanted plasmacytomas derived from primary hosts (2) and B-cell hybridomas (3). . growth of primary plasmacytomas (4) and B-cell hybrids immediately after fusion (5) requires the addition of “feeder” cells to the culture medium. In previou
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