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Titlebook: Mechanisms in B-Cell Neoplasia; Workshop at the Nati Fritz Melchers,Michael Potter (Chief) Conference proceedings 1986 The Editor(s) (if ap

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Transformation and Insertional Mutagenesis In Vitro of Primary Hematopoietic Stem Cell Culturestly reduced latency. Moreover, mice inoculated with J-2 virus generally die of multiple neoplasias. However, all neoplasms induced by this recombinant virus were clonal or oligoclonal in nature, suggesting that even the deregulated expression of two oncogenes was perhaps insufficient to maintain the
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Mammalian Cell Transformation by a Recombinant Murine Retrovirus Containing the Avian Erythroblastosavian virus into mammalian cells. Therefore, we constructed a recombinant v-.-containing murine retrovirus which has allowed for more extensive investigation of the function of this EGF receptor-related gene as a transforming or growth-promoting gene in well defined mammalian systems.
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Structural Modification of c-, in Lymphoma and Leukemias a portion of c-. (Goff et al., 1980) including a region encoding a protein-tyrosine kinase which is essential to the oncogenic activity of A-MuLV (Prywes et al., 1983). The cellular protein product of c-., like that of v-., is an active protein kinase (Konopka et al., 1985; Ben-Neriah et al., 1986a).
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Mechanisms in B-Cell Neoplasia978-3-642-71562-4Series ISSN 0070-217X Series E-ISSN 2196-9965
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