Titlebook: Mechanisms and Emerging Therapies in Tremor Disorders; Giuliana Grimaldi,Mario Manto Book 20131st edition Springer Science+Business Media

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Rodent Models of Tremornts. Tremor is a principal symptom of neurological disorders such as essential tremor, Parkinson’s disease, and related disorders. Unfortunately, the actual pathophysiological mechanisms underlying tremor remain poorly understood, and thus no effective therapeutic strategies have been developed. The

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Physiologic Tremor drugs). Consequently, the study of physiologic tremor requires the use of sensitive motion transducers such as miniature accelerometers, gyroscopic angular velocity transducers, or force transducers. Muscle activity is recorded electromyographically, using skin electrodes for gross motor activity a

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Rest Tremorook for a rest tremor, the patient is seated with the upper limbs relaxed and the forearms on the thighs, or the patient is lying horizontally in complete repose. Rest tremor is typically in the 3–6 Hz frequency range (Fig. 7.1) and may reach high levels of severity. Rest tremor is usually asymmetri

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Postural Tremorsy disease. The objective of the current chapter is to discuss the specific characteristics of postural tremor in healthy controls and in different pathologies. We believe that postural tremor deserves some attention since limbs are rarely completely at rest. Accordingly, postural tremor may hide imp

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Isometric Tremorc, but one should keep in mind that any voluntary movement is accompanied by physiological tremor, which is believed to be necessary to facilitate fast voluntary motion. The borderline between pathological and physiological tremors is less strictly delineated than most clinicians wished to. This is

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