Titlebook: Mechanism of Action of Antimicrobial and Antitumor Agents; John W. Corcoran,Fred E. Hahn,K. L. Arora Book 1975 Springer-Verlag Berlin Heid

Corporeal

Kanchanomycin for neoplastic cells in culture at extremely low concentrations (.., 1963; .., 1965). In HeLa cell culture assays, it has a cytotoxic end point of 0.002 μg/ml and a cellular lethal end point of 0.05 μg/ml. In this system, kanchanomycin is more cytotoxic than streptonigrin, mitomycin C or actinomyci

脱水

Carcinogen

Quinacrine and Other Acridinesial antimalarial drugs (. and ., 1930), apparently patterned after successful antimalarials possessing alkyl side chains as, for example, pamaquine (. and ., 1960; The Acridines, A. ., 1966). Quinacrine was introduced clinically in April, 1932 (. and ., 1936), but despite rapid professional acceptan

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Quinoxaline Antibioticscule (..., 1961). These colorless antibiotics are derived from various species of Streptomycetes and are highly active against gram-positive bacteria. They also exhibit a cytotoxic effect on cultured cells. The antibiotics were shown to inhibit various experimental tumors (..., 1955; ..., 1959; . an

Bravura

Rifamycins and Other Ansamycinscts of rifampicin have also been summarized by ... (1971); ... (1972) and in the journal Drugs (Editorial staff, 1971). In the present report therefore, early data are dicussed only briefly. Detailed references can be found in the foregoing papers.

不朽中国

Thiaxanthenones: Miracil D and Hycanthonesively in the treatment of human schistosomiasis, have attracted modest interest in experimental cancer chemotherapy, and have become useful probes in the examination of some aspects of molecular biology.

大包裹

3′-Amino-3′-Deoxyadenosinecoma 180. It was, however, not active against any of the four ascitic tumors when given by the intravenous, subcutaneous or oral routes. The material showed no antimicrobial activity against several species of gram-positive and gram-negative bacteria, fungi and yeasts.

liaison

Implicit

群岛

Book 1975armacology and of their direct application to studies on the mode of action of drugs. The field of molecular biology itself was in its relative infancy during the preceding decade and the unique role played by many anti­ biotics in the development of our understanding of nucleic acid synthesis and f