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Titlebook: Matrix Metalloproteinase Inhibitors; Specificity of Bindi Satya Prakash Gupta Book 2012 Springer Basel AG 2012 Collagenase Inhibitors.Gelat

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书目名称Matrix Metalloproteinase Inhibitors
副标题Specificity of Bindi
编辑Satya Prakash Gupta
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概述Focus on quantitative structure-activity relationship of MMP inhibitors.Contains an overview of endogenous tissue inhibitors of MMPs and their biological relevance.Written by experts in the field.Incl
丛书名称Experientia Supplementum
图书封面Titlebook: Matrix Metalloproteinase Inhibitors; Specificity of Bindi Satya Prakash Gupta Book 2012 Springer Basel AG 2012 Collagenase Inhibitors.Gelat
描述.Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results in tissue degradation, producing a wide array of disease processes such as rheumatoid arthritis, osteoarthritis, tumor growth and metastasis, multiple sclerosis, congestive heart failure, and others. Thus MMP inhibitors are candidates for therapeutic agents to combat a number of diseases. . .The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases. The articles focus specifically on structure-activity relationships of all classes of compounds and on their modes of action and specificity of binding with the receptors based on experimental and theoretical studies. These studies constitute a valuable asset for all those involved in drug development. .
出版日期Book 2012
关键词Collagenase Inhibitors; Gelatinases; Hydroxamic Acids; MMPs; Vascular Disease
版次1
doihttps://doi.org/10.1007/978-3-0348-0364-9
isbn_softcover978-3-0348-0764-7
isbn_ebook978-3-0348-0364-9Series ISSN 1664-431X Series E-ISSN 2504-3692
issn_series 1664-431X
copyrightSpringer Basel AG 2012
The information of publication is updating

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Snehasikta Swarnakar,Amartya Mishra,Susri Ray Chaudhuri (Guha)s as Re. → ∞, or has involved approximate double-layered models for supersonic flow [2.70–2.72] with insufficient consideration of the basic flow structure in the shear-disturbance sublayer [2.73]. Consequently, there is a need for a more general theory at ordinary practical Reynolds numbers, applic
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Mange Ram Yadav,Prashant Revan Murumkar,Vishal Prakash Zambre the interaction between viscous and inviscid regions and the calculation of pressure, velocity and temperature characteristics as a function of geometry, angle of attack and Mach number. Rather more than half the papers were concerned with two-dimensional configurations and the remainder with wings
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Rajeshwar P. Verma involving the interaction between viscous and inviscid regions and the calculation of pressure, velocity and temperature characteristics as a function of geometry, angle of attack and Mach number. Rather more than half the papers were concerned with two-dimensional configurations and the remainder with wings978-3-662-09016-9978-3-662-09014-5
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Mina M. Benjamin,Raouf A. Khalilfield have also been successful provided separation was not present [210, 218]. Recently an asymmetric trailing-edge flow with a small separated zone was successfully predicted using the Navier—Stokes equations [220]. The ability to calculate trailing-edge flows with large separated zones remains to
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