Titlebook: Maternal Drug Use and Infant Congenital Malformations; Bengt Källén Book 2019 Springer Nature Switzerland AG 2019 birth defects.teratogeni

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Maternal Use of Prolactin Inhibitors or Sex Hormones and Infant Congenital Malformations,lopment is driven by androgens. In the present material, only very few exposures were found for these drug categories. Use of prolactin inhibitors or sex hormones is strongly linked to subfertility in the woman, and an increased malformation risk may be explained by a direct effect of subfertility,

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Maternal Use of Cytostatic/Cytotoxic Drugs or Endocrine Drugs for Malignancy and Infant Congenital ould be avoided. If inadvertent exposure occurs, one has to calculate with a fetal risk and the possibility of induced abortion (when available) should be discussed. When used as immune suppressants at other diseases (e.g., rheumatoid arthritis or immunological bowel disease), lower doses are usuall

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Maternal Use of NSAID Drugs and Infant Congenital Malformations,c defects after at least some NSAIDs and notably naproxen. There also seems to be an association between maternal use of the propionic acid derivatives ibuprofen and naproxen and infant cleft lip/palate, so far not seen for other NSAIDs. Avoidance of these drugs and notably naproxen in early pregnan

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978-3-030-17900-7Springer Nature Switzerland AG 2019

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