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Titlebook: Mass Spectrometry Imaging; Principles and Proto Stanislav S. Rubakhin,Jonathan V. Sweedler Book 2010 Springer Science+Business Media, LLC 2

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发表于 2025-3-21 18:27:41 | 显示全部楼层 |阅读模式
书目名称Mass Spectrometry Imaging
副标题Principles and Proto
编辑Stanislav S. Rubakhin,Jonathan V. Sweedler
视频video
概述Illustrates mass spectrometry imaging on the sub-cellular, cellular, tissue, and whole body levels.Presents comprehensive information on sample preparation, data acquisition, and data processing appro
丛书名称Methods in Molecular Biology
图书封面Titlebook: Mass Spectrometry Imaging; Principles and Proto Stanislav S. Rubakhin,Jonathan V. Sweedler Book 2010 Springer Science+Business Media, LLC 2
描述Mass spectrometry (MS) offers unmatched capabilities for the detection, characterization, and identification of a broad range of analytes.Mass spectrometry imaging (MSI) integrates MS data with information on the spatial distributions of the analytes, further enhancing the applicability of MS.In Mass Spectrometry Imaging: Principles and Protocols, expert practitioners from academia, industry, and the clinic contribute cutting-edge protocols describing the application of MSI to investigations of analyte localization in a variety of specimens, from microorganisms to plant and animal tissues.Divided into three sections, this volume presents the principles of MS, current and future trends of MSI, and qualitative and quantitative protocols to measure and identify endogenous metabolites and xenobiotics.An array of MSI approaches and technologies for characterizing peptide and protein distributions are described in detail.Written in the highly successful Methods in Molecular Biology™ series format, protocol chapters include introductions to their respective topics, lists of the necessary materials and reagents, and step-by-step, readily reproducible laboratory procedures.Also included are
出版日期Book 2010
关键词Analytes; Distribution of peptides and proteins; Distributions; MS imaging; Mass Spectrometry; Metabolite
版次1
doihttps://doi.org/10.1007/978-1-60761-746-4
isbn_softcover978-1-61779-696-8
isbn_ebook978-1-60761-746-4Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC 2010
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Coagulant
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发表于 2025-3-21 23:02:03 | 显示全部楼层
Cellular Imaging Using Matrix-Enhanced and Metal-Assisted SIMSsolution images of cholesterol and other membrane components can be obtained for single neuroblastoma cells and reveal subcellular details. Alternatively, in ME-SIMS, 2,5-dihydroxybenzoic acid electrosprayed on neuroblastoma cells allows intact molecular ion imaging of phosphatidylcholine (PC) and sphingomyelin (SM) at the cellular level.
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发表于 2025-3-22 03:53:26 | 显示全部楼层
Mass Spectrometry Imaging of Small Molecules Using Matrix-Enhanced Surface-Assisted Laser Desorptionsensitivity for most compounds. With aims of improving MS imaging resolution and sensitivity of low-mass species, we describe an experimental protocol using a hybrid ionization method, termed matrix-enhanced SALDI (ME-SALDI), to detect crucial low-mass species with their spatial distribution in mouse brain tissue.
GONG
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挥舞
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constitute
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发表于 2025-3-22 20:41:06 | 显示全部楼层
Imaging Mass Spectrometry: Viewing the Future specificity for MS-based detection makes IMS an effective discovery tool. Further structural assessment of compounds, including MS/MS fragmentation analysis, can be utilized in an imaging experiment to achieve accurate molecular identifications.
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发表于 2025-3-23 00:41:11 | 显示全部楼层
Lipid Detection, Identification, and Imaging Single Cells with SIMSwill describe sample preparation, data collection, and the analysis of lipids for two systems; rat oligodendrocytes and .. SIMS spectra yield information regarding lipid identity and concentration across cell surface.
AGATE
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发表于 2025-3-23 04:20:47 | 显示全部楼层
Mapping Pharmaceuticals in Rat Brain Sections Using MALDI Imaging Mass Spectrometryts major metabolite, desmethylastemizole, was only found around ventricle sites. We have shown that astemizole alone is likely to be responsible for the central nervous system (CNS) side effects when its exposures became elevated.
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发表于 2025-3-23 07:15:38 | 显示全部楼层
1064-3745 ™ series format, protocol chapters include introductions to their respective topics, lists of the necessary materials and reagents, and step-by-step, readily reproducible laboratory procedures.Also included are978-1-61779-696-8978-1-60761-746-4Series ISSN 1064-3745 Series E-ISSN 1940-6029
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