Titlebook: Management of Early Stage Breast Cancer; Basics and Controver Beena Kunheri,D. K. Vijaykumar Book 2021 Springer Nature Singapore Pte Ltd. 2

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Sentinel Lymph Node in Early Breast Cancer: Evidence, Techniques, and Controversies,-conservative approaches. Regional management of breast cancer has also evolved with sentinel lymph node biopsy (SLNB) becoming the “evidence-based standard” in clinically appropriate settings. In this chapter, we will trace the evolution and incorporation of SLNB in early breast cancer.

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Molecular Mechanisms of Early Breast Cancer,cell type. The process can extend from understanding the driver and passenger genetic alterations to actionable alterations in coherent cell signaling pathways. One of the major factors for complexity is molecular heterogeneity in cancer. Molecular heterogeneity can be within different clones of cel

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Surgical Management of Early Breast Cancer, carcinoma in situ and stage I, stage IIA, stage IIB and stage IIIA breast cancers. Early-stage breast cancers are potentially curable and always include surgical removal of breast tumour and axillary nodes. Surgery alone will result in long-term survival for a select group of patients, depending on

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Sentinel Lymph Node in Early Breast Cancer: Evidence, Techniques, and Controversies,xtravasated fluid from the interstitium [1]. In tumors, the lymphatics act as a conduit for transport of tumor cells to regional nodes, which in turn might facilitate systemic seeding [2]. The biological understanding of breast cancer has progressed from a purely “mechanistic model” (forming the bas

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Oncoplastic Surgery in Early Breast Cancer,ement associated with surgery. In breast conservation surgery, where the surgeon has to excise >20% of the breast volume, the cosmetic outcomes are less than optimal. Oncoplastic surgery (OPS) combines techniques used in plastic surgery with the oncology principle of resecting the tumour with adequa

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Risk Stratification for Adjuvant Treatment in Early Breast Cancer,ographic screening, reflex biopsy of calcifications, and the landscape of breast cancers being seen in the clinics have drastically changed from presentation with advanced breast cancers to a current situation of majority patients reporting with early breast cancer. Given the amount of research data