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Titlebook: Mammary Tumor Cell Cycle, Differentiation, and Metastasis; Advances in Cellular Robert B. Dickson,Marc E. Lippman Book 1996 Kluwer Academic

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书目名称Mammary Tumor Cell Cycle, Differentiation, and Metastasis
副标题Advances in Cellular
编辑Robert B. Dickson,Marc E. Lippman
视频video
丛书名称Cancer Treatment and Research
图书封面Titlebook: Mammary Tumor Cell Cycle, Differentiation, and Metastasis; Advances in Cellular Robert B. Dickson,Marc E. Lippman Book 1996 Kluwer Academic
描述.Mammary Tumor Cell Cycle, Differentiation and Metastasis.is the fifth volume since 1988 in a series designed to broadly examinecurrent advances in the cellular and molecular biology of breastcancer. As in previous volumes, the editors have invited recognizedexperts in cutting-edge topics to provide a chapter focused on theirarea of research. The editors have turned to the researchers who studyrodent models of the disease and to those who study the cellular andmolecular basis of human breast cancer. .The first section of the book is devoted to new mouse models ofmammary development and tumorigenesis. The second section moves tostudies of human breast cancer and focuses on receptors, signalling,and the cell cycle. The final section deals with defective tissueinteractions in human breast cancer. .We are now in a period of extremely rapid accumulation of data on themolecular and cellular biology of breast cancer. These findings arehighlighted in chapters from .Mammary Tumor Cell Cycle,Differentiation. .and Metastasis: Advances in Cellular andMolecular Biology of Breast. .Cancer..
出版日期Book 1996
关键词angiogenesis; biology; cell; cell death; development; immunology; metastasis; molecular biology; oncogene; pr
版次1
doihttps://doi.org/10.1007/978-1-4613-1259-8
isbn_softcover978-1-4612-8536-6
isbn_ebook978-1-4613-1259-8Series ISSN 0927-3042 Series E-ISSN 2509-8497
issn_series 0927-3042
copyrightKluwer Academic Publishers 1996
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Role of the nuclear matrix in breast cancerral oncogenes. Defining how the nuclear matrix is involved in the process of cell transformation has implications not only for understanding malignancy, but also for the development of new biomarkers for diagnosis and prognosis.
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Programmed cell death and mammary neoplasiad toward understanding the role of cell proliferation in neoplastic development, much less is known about the process of apoptotic cell death in either the control of normal tissue homeostasis or its potential influence on neoplastic development.
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Tissue reconstitution, or transgenic mammary gland, technique for modeling breast cancer developmentowth pattern? How do clones of cells that express an oncogene behave among neighboring normal cells in an epithelium? The method also allows sequential introduction of more than one oncogene to follow tumor development.
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Antiestrogen-estrogen receptor interactionsIGF-I) and epidermal growth factor (EGF) [5,6], they might function by increasing the sensitivity of cells to growth factors produced either by tumor cells themselves or perhaps by surrounding stromal cells, thereby regulating cell proliferation by a paracrine mechanism [7].
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