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Titlebook: Mammary Tumor Cell Cycle, Differentiation, and Metastasis; Advances in Cellular Robert B. Dickson,Marc E. Lippman Book 1996 Kluwer Academic

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Wei-Ping Ren,Bonnie F. Sloane. und XI. Reihe) finden wir im wesentlichen alle die Erscheinungen beschrieben, mit denen wir es in dem vorliegenden Kapitel zu tun haben. Freilich können wir, ohne minder umfassend zu sein, auf wenigen Seiten heute den Inhalt der vielen Beobachtungen . darstellen, indem wir eine zuverlässige Theori
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Tissue reconstitution, or transgenic mammary gland, technique for modeling breast cancer development have introduced tumor mutations into individual clones of cells in mouse mammary epithelium, in mice, by a transplantation approach known as . or constructing a .. Introducing oncogenes and growth factor genes in this way has shown how the three-dimensional growth pattern of mammary epithelium is a
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Preneoplasia in mammary tumorigenesis experimental observations over the past 40 years in practically all major epithelial organs [1–3]. The intermediate stages have been labeled with various terms, the most common terms being . or .. Recently it has been recognized that the stage of preneoplasia itself represents a progression of seve
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Protein kinase C and breast cancerhed the importance of PKC activity in a multitude of cell functions that regulate growth and differentiation in a variety of cell types [4,5]. More recently, molecular cloning approaches have established that PKC is actually a family of closely related isoenzymes [6,7]. These include the calcium-dep
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Protein tyrosine phosphataseseration, differentiation, and neoplastic transformation [1–4]. The net cellular level of tyrosine phosphorylation is maintained dynamically by the opposing actions of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPases). While the involvement of PTKs in these cellular processe
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Role of the nuclear matrix in breast cancers organized by the nuclear matrix, the RNA-protein skeleton of the matrix. The nuclear matrix is the scaffold that organizes DNA at a structural as well as a functional level [1]. By organizing DNA in both structural and functional manners, the nuclear matrix plays a critical role in normal cellular
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