Titlebook: Macrophages; Origin, Functions an Malgorzata Kloc Book 2017 Springer International Publishing AG 2017 Macrophage.Phagocytosis.Immune respon

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Macrophages and Their Contribution to the Development of Atherosclerosisdevelopment of local inflammatory response and atherosclerotic lesion growth. Atherosclerotic plaque is a complex microenvironment, in which different subsets of macrophages coexist executing distinct, although in some cases overlapping functions. According to the classical simplified nomenclature,

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Macrophage Dysfunction in Respiratory Diseasenvironment. However, in respiratory diseases including chronic obstructive pulmonary disease (COPD), asthma, and cystic fibrosis, macrophages appear to be dysfunctional and may contribute to disease pathogenesis. In COPD, phagocytosis of bacterial species and apoptotic cells by both alveolar macroph

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Hofbauer Cells: Placental Macrophages of Fetal Origin Despite a growing body of evidence that these cells are important, our knowledge about Hofbauer cell function in both normal and dysfunctional pregnancy is rudimentary. The goal of this chapter is to provide an overview of what is known about Hofbauer cell origins and their potential roles in norma

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Mesenchymal Stem Cells Direct the Immunological Fate of Macrophagess such as PGE., IL1RA, and IL-6. Moreover, the presence of macrophages in damaged tissue and inflammation is essential for MSC to exert their therapeutic function. In this chapter, we discuss how the interplay between macrophages and MSC mutually modulates their phenotypes and functions, orchestrate

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Role for Mechanotransduction in Macrophage and Dendritic Cell Immunobiologying that key immune effector functions are altered by mechanical stimuli. In this chapter, we describe the different types of mechanical signals that cells encounter within the body and review the current knowledge on the role of mechanical signals in regulating macrophage, monocyte, and dendritic c