Titlebook: Macrophage Targeted Delivery Systems; Basic Concepts and T Swati Gupta,Yashwant V. Pathak Book 2022 The Editor(s) (if applicable) and The A

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Yubin Li,Xuyao Zhang,Xian Zeng,Shaofei Wang,Hongbin Wang

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Largee Biswas,Monika Yadav,Priyanka Singh,Sushma Talegaonkar,Anita Kamra Verma

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Introduction to Pharmacology of Macrophages with Drug Delivery Perspective, sepsis, metabolic disorders, atherosclerosis, inflammatory diseases, etc. suggests that macrophages can play a detrimental role as well. Being key players in homeostasis, host defense, and disease, they can also be possible targets for therapeutic applications. Developing novel strategies to targe

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Understanding Macrophage-Associated Diseases and Applications of Nanodrug Delivery Systemsr therapies, such as inhibition of tumor-associated macrophage (TAMs) recruitment, reeducation, and direct killing. Recently, investigations were done on targeting tumor macrophages with therapeutic drugs loaded with nanomedicines called live cell-mediated drug delivery systems (LCDDS) for transport

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Polymeric Nanoparticles-Assisted Macrophage Targeting: Basic Concepts and Therapeutic Goalsic macrophage receptors (including activin, CD44, and toll-like receptors) to achieve improved therapeutic effect. Redesigned (genetically modified) and reeducated (tumor-associated macrophages TAMs) macrophages have also been developed to meet the desired clinical effects. This chapter aims to comp

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Polymeric Nanoparticles-Based Drug and Gene Delivery to Macrophageske macrophages. Conversely, cancer is associated with increased infiltration and/or activity of the immunosuppressive and tumor-promoting M2-like macrophages, including tumor-associated macrophages (TAMs), and polymeric nanoparticles have been designed to deplete the M2-like macrophages or repolariz

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Surface Modification of Nanoparticles for Macrophage Targetingchieved through numerous nanodelivery systems such as niosomes, carbon nanotubes, liposomes, and dendrimers and has been explored for their drug delivery and therapeutic potential..Further, these nanosystems are surface modified to improve the delivery of drugs and therapeutic efficacy of targeting.

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Liposomal Delivery for Targeting Macrophages drugs to target macrophages for the treatment of infection, inflammation, cancers, cardiovascular diseases, cerebral ischemia and stroke, etc. Phospholipid composition, particle size, surface charge, and modified surface are major factors affecting the efficacy of liposomes as a drug delivery syste