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Titlebook: Macrophage Targeted Delivery Systems; Basic Concepts and T Swati Gupta,Yashwant V. Pathak Book 2022 The Editor(s) (if applicable) and The A

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Solid Lipid Nanoparticles-Based Drug and Gene Delivery to Macrophagesnd various types of methods of preparation are discussed in this chapter along with the application of SLNs in targeting macrophages. Also, the current scenario of SLNs’ application for targeted therapy to enhance its targetability and internalization is discussed in this chapter.
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Introduction to Pharmacology of Macrophages with Drug Delivery Perspectiveid host defense by inducing inflammation, exhibiting microbicidal and tumoricidal properties, controlling the activation of adaptive immunity, alleviating inflammation, and boosting tissue repair while also performing important trophic functions in organs/tissues (such as brain, mammary glands, bone
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Mechanisms and Ways of Macrophage Deliveryed toward either M1, which promotes inflammation, or M2, which inhibits inflammation through anti-inflammatory cytokines. Phagocytosis is the capability to destroy foreign pathogens by cellular degradation through lysosomes. A phagosome is formed around the target substance and releases components t
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Macrophage-Associated Disorders: Pathophysiology, Treatment Challenges, and Possible Solutionss in treatment for immune system ailments is the imprecise targeting of therapeutic molecules to the ideal cells due to a lack of insights into disease pathophysiology prompting deficient therapeutic viability. The activated macrophages are chieftain in immune reaction safeguarding the body from una
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Polymeric Nanoparticles-Based Drug and Gene Delivery to Macrophagese degeneration due to secondary injury, and cancer are associated with increased infiltration and/or activity of a specific macrophage phenotype. Conseqently, different types of nanoparticles have been designed for macrophage-targeted drug/gene delivery, and polymeric nanoparticles emerged as one of
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Liposomal Delivery for Targeting Macrophagesnot only for the treatment but also for the prevention of the diseases. Different approaches in nanoparticles have been explored in macrophage-targeting macrophages for cancer therapy. Liposomes, a type of nanocarrier, are a promising candidate for the delivery of drug targeted to macrophages for ma
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