书目名称 | MRI Contrast Agents | 副标题 | From Molecules to Pa | 编辑 | Sophie Laurent,Céline Henoumont,Luce Vander Elst | 视频video | | 概述 | Includes supplementary material: | 丛书名称 | SpringerBriefs in Applied Sciences and Technology | 图书封面 |  | 描述 | .This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc. . | 出版日期 | Book 2017 | 关键词 | Imaging Probes; Iron Oxide Nanoparticles; MRI Contrast Agents; Nanomaterials in Medicine; Nanoparticles | 版次 | 1 | doi | https://doi.org/10.1007/978-981-10-2529-7 | isbn_softcover | 978-981-10-2527-3 | isbn_ebook | 978-981-10-2529-7Series ISSN 2191-530X Series E-ISSN 2191-5318 | issn_series | 2191-530X | copyright | The Author(s) 2017 |
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