Titlebook: MHC Protocols; Stephen H. Powis,Robert W. Vaughan Book 2003 Springer Science+Business Media New York 2003

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HLA-DPA1 and -DPB1 Typing Using the PCR and Nonradioactive Sequence-Specific Oligonucleotide Probesarm of chromosome 6 in the HLA-D region. These molecules consist of an α and ß chain that associate as heterodimers on the surface of antigen presenting cells. They serve as receptors for processed peptides derived primarily from mem-brane and extracellular proteins that they present to CD4. lymphoc

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Complement C4 Protein and DNA Typing Methodsh a steroid 21-hydroxylase (CYP21) gene at its 3′ end, together with the genes for C2 and factor B in the major histocompatibility complex (MHC) class III gene region between HLA-B and human leukocyte antigen (HLA)-DR (.). C4 polymorphism can be defined at three levels: (i) at the genomic level rega

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Typing of Tumor Necrosis Factor Allelesof the class III region of the major histocompatibility complex (MHC) approximately 1 megabase telomeric to the human leukocyte antigen (HLA)-DR locus and 250 kb centromeric to HLA-B. In view of the potent biological activites of these molecules and the location of their genes within the MHC, the po