Titlebook: Lymphoproliferative Diseases; D. B. Jones,D. H. Wright Book 1990 Kluwer Academic Publishers 1990 cell.classification.diseases.immunoglobul

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Analysis of Immunoglobulin Changes in Lymphoproliferative Diseases,on-immunoglobulin determinants and used for the characterization of B-cells at various stages of differentiation. Essentially the Ig molecule is a four chain structure composed of two light chains and two heavy chains, with the carboxy terminal sequences of the heavy chains determining whether the m

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Immunoenzymatic Analysis of Haematological and Cytological Preparations,ological disorders. Lymphomas and leukaemias may also be complicated by pleural and peritoneal effusions. A cytological examination of serous fluid often clarifies a diagnosis which would otherwise be obscure. However, in many cases it is difficult even for the experienced haematologist or cytologis

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Cell-mediated Immunity in Lymphomas,ed cutaneous hypersensitivity (DCH). Subsequently, Parker (1932) confirmed this lack of a tuberculin reaction in most patients with Hodgkin’s disease, and suggested that their susceptibility to tuberculosis may be due to an immunological deficit. In those days Hodgkin’s disease was so commonly assoc

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The Origin of the Reed-Sternberg Cell,s in our ability to investigate human cell types. From the development of the most basic techniques in histopathology we have advanced to a stage where genes, or segments of genes responsible for a particular phenotypic expression can be examined in minute detail. Despite considerable effort over th

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T-cell Neoplasia, It is unclear whether the stem cell is committed to becoming a T-cell before this processing, or if the thymus itself induces T-cell differentiation. During development, at around 8 weeks gestation, the thymus gland, which is initially epithelial in nature, becomes filled with lymphoid cells. Lymph

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