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Titlebook: Lymphoma; Tim Illidge,Peter W. M. Johnson Book 2005 Humana Press 2005 DNA.biopsy.chemistry.leukemia.lymphoma

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书目名称Lymphoma
编辑Tim Illidge,Peter W. M. Johnson
视频video
概述Includes supplementary material:
丛书名称Methods in Molecular Medicine
图书封面Titlebook: Lymphoma;  Tim Illidge,Peter W. M. Johnson Book 2005 Humana Press 2005 DNA.biopsy.chemistry.leukemia.lymphoma
描述A cutting-edge collection of readily reproducible molecular techniques to better understand, classify, and treat lymphoma. Among the highlights are methods to use immunoglobulin gene rearrangements as markers of clonality, to exploit patterns of somatic mutation in the variable regions to indicate at which stage transformation occurred, and to apply gene arrays to the question of biological heterogeneity in morphologically similar diseases. Research methodologies that are highly likely to become routine practice in the future, such as DNA microarray and immunoglobulin V-gene rearrangements, and measurement of minimal disease, are included. There are also molecular techniques for providing for producing novel therapeutics, such as a DNA vaccine with patient-specific sequences derived from the lymphoma in question.
出版日期Book 2005
关键词DNA; biopsy; chemistry; leukemia; lymphoma
版次1
doihttps://doi.org/10.1385/1592599362
isbn_softcover978-1-61737-395-4
isbn_ebook978-1-59259-936-3Series ISSN 1543-1894 Series E-ISSN 1940-6037
issn_series 1543-1894
copyrightHumana Press 2005
The information of publication is updating

书目名称Lymphoma影响因子(影响力)




书目名称Lymphoma影响因子(影响力)学科排名




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书目名称Lymphoma网络公开度学科排名




书目名称Lymphoma被引频次




书目名称Lymphoma被引频次学科排名




书目名称Lymphoma年度引用




书目名称Lymphoma年度引用学科排名




书目名称Lymphoma读者反馈




书目名称Lymphoma读者反馈学科排名




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Follicular Lymphoma,s not yet possible to determine whether the detection of residual lymphoma cells by PCR is an indication to continue therapy. Therefore, although these techniques provide a useful adjunct to standard methods of detection and diagnosis, their role in staging of disease outcome remains investigational.
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Molecular Diagnosis of Lymphoma,and outcome using microarray technology were generated using DLBCL samples and are described. The different types of microarray platform and data analysis tools are reviewed followed by a detailed step-by-step guide to data generation using the Affymetrix chip system from RNA extraction to laser scanning of the hybridized and stained chips.
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Cloning of Immunoglobulin Chromosomal Translocations by Long-Distance Inverse Polymerase Chain Reacning. We discuss in this chapter the use of long-distance inverse polymerase chain reaction methods to clone immunoglobulin chromosomal translocation breakpoints from clinical material. These methods have been successfully applied to several other types of chromosomal translocation including those involving other genes such as ., ., and ..
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Antibody Techniques Used in the Study of Anaplastic Lymphoma Kinase-Positive ALCL,cal category of anaplastic large cell lymphoma. Antibody techniques have also provided major new insights into the biology of these tumors. This chapter describes the use of antibodies in both immunolabeling (immunocytochemical and immunofluorescence) procedures and in biochemical procedures in the study of ALK-positive ALCL.
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,Karyotyping Lymph Node Biopsies in Non-Hodgkin’s Lymphoma,g with hints on how to correct any problems encountered on initial staining. We also describe how to prepare this material for fluorescence . hybridization techniques, both for further delineation of complex chromosomal rearrangements and for interphase analysis in cases in which conventional cytogenetics has not been successful.
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