Titlebook: Lymphocyte Hybridomas; Second Workshop on “ F. Melchers,M. Potter,N. L. Warner Conference proceedings 1979 Springer-Verlag Berlin Heidelber

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978-3-540-09670-2Springer-Verlag Berlin Heidelberg 1979

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Anti-Viral and Anti-Tumor Antibodies Produced by Somatic Cell Hybrids, have aided us in studies of: a) the antigenic determinants of a number of viruses, b) transforming proteins in cells transformed by oncogenic viruses, c) antigens expressed by human tumor cells and d) the genetics of antibodies.

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Hybrid Plasmacytoma Production: Fusions with Adult Spleen Cells, Monoclonal Spleen Fragments, Neonaress in many areas of biology and immunochemistry. In general it will make possible advances in at least two areas: 1) analysis of the mouse B-cell repertoire and 2) production of monoclonal antibodies to be used as reagents. We will describe here the methods we have used to make progress in both of these areas.

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