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Titlebook: Lung Inflammation in Health and Disease, Volume I; Yong-Xiao Wang Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusi

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https://doi.org/10.1007/978-3-030-63046-1Asthma; Pulmonary Hypertension; endothelial cells; fibroblasts; lymphocytes; neutrophils; microbiota; COPD;
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Potential Role of Mast Cells in Regulating Corticosteroid Insensitivity in Severe Asthma,ing a key role of mast cells in the poor response of patients to these drugs. The present chapter will discuss the possible underlying mechanisms by which mast cells could contribute to reducing corticosteroid sensitivity seen in patients with severe asthma.
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Hypercapnic Respiratory Failure-Driven Skeletal Muscle Dysfunction: It Is Time for Animal Model-Basadvocates for the development of a syndromic model in which skeletal muscle dysfunction is investigated as a comorbidity of a well-validated pulmonary disease model, which could potentially allow discovering meaningful mechanisms and pathways and lead to more substantial progress to treat this devastating condition.
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Crosstalk Between Lung and Extrapulmonary Organs in Infection and Inflammation,s on how pneumonia may lead to a systemic pathophysiological response to acute lung injury and chronic lung disease through organ interactions, which can facilitate the development of undesirable and even deleterious extrapulmonary sequelae.
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