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Titlebook: Lung Development; Claude Gaultier,Jacques R. Bourbon,Martin Post Book 1999 American Physiological Society 1999 Lung Development.circulatio

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Gene Expression in Alveolar Development,s known as . and . or . and .. The former is a flat, attenuated, terminally differentiated cell through which air—blood gas exchanges occur. The latter is a cuboidal cell that elaborates and releases all the phospholipid and protein components of pulmonary surfactant (87, 113); it also serves as a p
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Development of the Pulmonary Vasculature,te the cardiac output of the fetal heart which begins to beat as early as the 14th day of gestation in humans. Since the endothelial cell defines the lumen of the developing vasculature, it can be said to be one of the first cells in the organism to acquire a specialized function. The continued grow
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Nitric Oxide and Endothelin in the Developing Pulmonary Circulation: Physiologic and Clinical Implienfold and enables the lung to assume its postnatal role in gas exchange. Failure of the pulmonary circulation to successfully achieve and sustain this decrease in PVR causes severe hypoxemia in many neonatal cardiopulmonary disorders, which are referred to as the syndrome persistent pulmonary hyper
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Development of Cellular Host Defense Mechanisms,hematological defenses provided by leukocytes and their products acting in the lungs. Various mechanisms are used in these defenses, and they come into being at different times during lung development as effector cells differentiate. In general, operation of all such defenses improves as cells becom
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Bioactive Peptides and Lung Development,d other epithelial cells in developing lung. Lung development is a complex process involving multiple interactions between different cell types and secreted factors; among these, epithelial—mesenchymal interactions have been most extensively studied. Cellular processes occurring during this process
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