Titlebook: Lung Cancer Metastasis; Novel Biological Mec Venkateshwar Keshamouni,Douglas Arenberg,Gregory K Book 2010 Springer-Verlag New York 2010 ang

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Chemokines in Lung Cancer Metastasis,biological processes, including control of cancer angiogenesis and mediating homing of metastatic cells. In this chapter, we review the role of chemokines in angiogenesis and angiostasis and metastasis in the context of lung cancer.

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Tumor Stem Cells and Metastasis, of lung cancer. This chapter will discuss the emerging data supporting the validity of this notion and consider the growing evidence that cancer stem cells may contribute to tumor progression, drug resistance, metastasis, and speculates about how taking these cells into consideration may affect the way we treat lung cancer in the future.

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Angiogenesis and Angiogenic Diversity in Lung Cancer Metastasis,gnature of each tumor’s microenvironment [7, 8]. This chapter will focus on the basic cellular mechanisms of angiogenesis, followed by a discussion of various factors that are involved in lung cancer angiogenesis, and the clinical implications of the diversity of angiogenic pathways in cancer.

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Book 2010ed deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book are a) to introduce clinical aspects to basic scientists and basic molecular and cellular concepts to clinical investigators, in order to promote collab

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Biomarker Discovery for Metastatic Disease,ators), and proteins in primary and metastatic tumors, in proximal biofluids, and in the blood plasma generates potentially complementary molecular signatures. We illustrate the use of Oncomine and Molecular Concepts Maps and the biological amplification of tumor protein signals with immune .

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Hallmarks of Metastasis,tates a detailed understanding of the molecular and cellular mechanisms behind each of these steps. In this chapter, we will discuss hallmarks of metastatic process, along with theories proposed, genes involved, techniques to monitor, and therapeutic implications.

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