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Titlebook: Low Dose Oral and Transdermal Therapy of Hypertension; Michael A. Weber,Jan I. M. Drayer,R. Kolloch Conference proceedings 1985 Springer-V

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Transdermal Clonidine in Elderly Patients with Mild Hypertension: Effects on Blood Pressure and Plarapy does not significantly change fluid volumes, cardiac haemodynamics or renal function (Thananopavarn et al. 1982). Additionally, the potentially disadvantageous changes in lipid chemistry that have been seen with diuretic and .-blocking drugs have not been reported with clonidine. The developmen
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Diabetes and Hypertension: Clonidine Monotherapy,ing so-called essential hypertension partly related to the frequent occurrence of obesity in the diabetic population, and also perhaps reflecting relative expansion of the extracellular fluid space (de Chatel et al. 1977) or poor compliance of large vessels in turn producing high systolic blood pres
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Low Dose Oral and Transdermal Application of Clonidine in Mild Hypertension: Hemodynamic and Biocheose-response relationship for clonidine are only available for the range from 0.300 to 0.750 mg/day (8, 10, 17). In this range, also described as a therapeutic window, there is a close relationship between the hypotensive effect and an increase of the side effects such as sedation and reduced saliva
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Regression of Left Ventricular Hypertrophy in Nineteen Hypertensive Patients Treated with Clonidineted both from animal and clinical studies that LVH occurs quite early as a cardiac response to hypertension and indeed occurs at a greater frequency (40–50% of mild to moderate cases) than had been previously anticipated by electrocardiographic studies (2–5%) of similarly hypertensive patients. Rece
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Pharmacodynamics and Pharmacokinetics of Oral and Transdermal Clonidine in Chronic Renal Insufficiea of cardiovascular medicine (Adkinson 1977; Karsh et al. 1978; Hansen et al. 1979; Müller et al. 1982; Colfer et al. 1982; Olivari and Cohn 1983). Although some controversy exists now about bioavailability and effectiveness, it still remains a viable alternative to sublingual and oral administratio
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A Multicenter Study on the Use of Transdermal Clonidine in Patients with Essential Hypertension,). In these patients, blood pressure is often controlled using oral therapy with a single agent. Recently, a new delivery system for monotherapy with the centrally-acting sympatholytic agent clonidine has become available. In this study, we describe the results of a multicenter study using an adhesi
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