Titlebook: Long Non-coding RNAs in Human Disease; Kevin V. Morris Book 2016 The Editor(s) (if applicable) and The Author(s), under exclusive license

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Long Non-coding RNA , and , in Human Cancers and Cardiovascular Disease,o regulate additional loci in .. This action would further increase the complexity for mechanisms imposed through . and furthering the scope of this lncRNA in disease pathogenesis. In this chapter, we summarize the most recent findings on the investigation of . and provide a perspective on the biolo

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Form and Function of Exosome-Associated Long Non-coding RNAs in Cancer,ether to disseminate cell signals that alter and/or control local cellular microenvironments. This review will identify the various roles that lncRNAs and exosomes play in cancer development, as well as the possibility that exosomes may transfer functional lncRNAs between cells as a means of cell-to

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Noncoding Transcriptional Landscape in Human Aging,, the role of long noncoding RNAs (lncRNAs) as regulators of gene expression might be important for the overall transcriptional landscape observed in aged human cells. The possible functions of lncRNAs and other noncoding RNAs, and their roles in the regulation of aging-related cellular pathways wil

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Expression Specificity of Disease-Associated lncRNAs: Toward Personalized Medicine,‚ antisense lncRNAs‚ and repetitive elements. Results from FANTOM project enable assessment of lncRNA expression specificity across tissue and disease conditions‚ based on differential promoter and enhancer usage. More than 85 % of disease-related SNPs are within noncoding regions and are strikingly

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