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Titlebook: Local Immunosuppression of Organ Transplants; Scott A. Gruber Book 1996 Springer-Verlag Berlin Heidelberg 1996 drug.drug delivery.drug dev

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楼主: cucumber
发表于 2025-3-26 21:50:07 | 显示全部楼层
Site-Specific Immunosuppression with Topical Agents their powerful ability to permanently alter immune responsiveness, in comparison to conventional agents, so that some degree of selective immunologic nonreactivity can be achieved. Therefore, it would be extremely advantageous to develop topical formulations of novel immunosuppressants for localized site-specific action..
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Book 1996els using osmotic minipumps for delivery of a variety of immunosuppressants. The book will be of great benefit to researchers in the fields of transplant immunology, pharmacology and drug delivery and targeting, particularly those involved in drug development.
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1080-3645 ograft models using osmotic minipumps for delivery of a variety of immunosuppressants. The book will be of great benefit to researchers in the fields of transplant immunology, pharmacology and drug delivery and targeting, particularly those involved in drug development.978-3-662-22107-5978-3-662-22105-1Series ISSN 1080-3645
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Local Regulation of Allograft Rejectionrug-targeting systems for achieving local immunosuppression. This chapter will review the available data in support of the first hypothesis by detailing the evidence for and the mechanisms of local regulation of allograft rejection.
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Intrarenal Administration of Anti T Cell-Monoclonal Antibodyn the graft makes the transplanted organ a favorable object for local immunosuppressive therapy. Therefore, we investigated the efficacy of local administration of anti-T cell MoAb via the renal artery in a rat kidney transplant model, with the hope of increasing its antirejection effect and decreasing toxicity.
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Pharmacokinetic Advantage of Regional Drug Deliveryed in several reports.. The theory states that arterial infusion may provide increased drug delivery to the target organ and decreased drug delivery to the systemic circulation when compared with same-dose intravenous (i.v.) administration, and is based on two assumptions: (1) the kinetics of drug d
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Early Studies of Local Immunosuppression (1964–1984) et al. treated rabbit skin allografts with 5 mg of cortisone acetate suspended in 0.2 ml of saline with 1.5% benzyl alcohol. This suspension was applied directly to the grafted skin every third day, beginning immediately before the grafts were placed on the prepared site. The topical application of
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