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Titlebook: Liver Immunology; Principles and Pract M. Eric Gershwin,John M. Vierling,Michael P. Manns Book 20071st edition Humana Press 2007 Antigen.au

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Cytokines in Liver Health and Diseaseal processes in and around the cells that produce them. They may act on different cell types (pleiotropic effects) and have overlapping effects (redundancy); furthermore, their action may be local or systemic. In most tissues, including the liver, constitutive production of cytokines is absent or mi
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Prevalence and Significance of Autoantibodies in Acute and Chronic Liver Diseases and Hepatocellularures, which can originate from different subcellular compartments (.–.). Autoantibodies have been described that target membrane-bound proteins of the cell and nuclear membranes and that reside in the cytoplasm or in other organelles such as the endoplasmic reticulum (Table 1) or mitochondria (Table
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The Role of Inflammation and Immunity in the Pathogenesis of Liver Fibrosis this wound-healing response has led to realistic expectations for treating fibrosis in patients with chronic liver disease owing to either viral hepatitis or metabolic or autoimmune diseases, among others. There has been continued clarification of the cellular source of extracellular matrix (ECM) i
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Clinical Use of Immunopathology Techniques in Liver Diseasesstances, engages in bile formation for the elimination of amphiphilic and water-insoluble molecules from the body, and constitutes a unique immunological site. Its location astride the spanchnic and systemic circulation creates a critical role for immunological processing of antigens in the splanchn
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Innate and Adaptive Immune Responses to Bacterial and Parasite Infectionsnfect 1.6 billion people worldwide or approximately one-third of the world’s population, killing about 3 million people each year (.,.). More than 90% of tuberculosis (TB)-related deaths occur in developing countries, and the disease has huge social and economic costs. Nations with a high prevalence
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Immune Response to Hepatitis A and E Viruses of viral hepatitis worldwide. In the United States, the number of notified cases annually is around 23,000, but estimates of the real number of cases of clinical disease range up to 75,000 per year. The infection is usually transmitted via a fecal-oral route and is associated only with acute forms
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Immune Responses in Acute and Chronic Hepatitis Ct impressive examples in modern medicine in which a combination of expertise from very different fields helped to identify the cause of a major disease and led to the development of effective therapies.
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