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Titlebook: Liposome Dermatics; Griesbach Conference Otto Braun-Falco,Hans Christian Korting,Howard I. Conference proceedings 1992 Springer-Verlag Ber

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Basic Principles of Liposomes for Drug Useor parenteral administration as the drug circulates to all organs of the body in the blood. These problems may be circumvented by the use of “carriers” which deliver drugs to the areas of the body in need of more localized pharmacological intervention. Such carriers protect the drug against hostile
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Phospholipids as Basic Ingredientsl, the .-1 and .2 positions of the glycerol residue being esterified with fatty acids of varying length and degree of unsaturation, while the .-3 position is esterified with phosphoric acid. The “basic” compound of phospholipids is phosphatidic acid, which carries only the phosphate as a hydrophilic
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Ceramides for Liposomesresearch activities [4, 7, 9, 12, 16, 17, 18, 19, 20]. Of special interest is the function of glycosphingolipids as cell-surface antigens, as in the Lewis antigen A-D determinants or the well-known H, A, B blood group determinants. Also, glycosphingolipids which accumulate in the surface of cancer c
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Liposome Phospholipids: Toxicological and Environmental Advantagesre the natural building blocks for cell membranes and are recognised as “pseudo-self” molecules, with low allergenic potential. They can be metabolised in a similar manner to endogenous membrane phospholipids and have the particular advantage of wide structural variability, which can be utilised to
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Monitoring in vivo Skin Hydration by Liposomes Using Infrared Spectroscopy in Conjunction with Tape s, using Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy..The liposomes proved to be superior to the non-liposomal preparation in driving deuterium oxide . the stratum corneum, but were unable to accumulate as much hydrogen oxide as their non-liposomal counterpart. Both effects
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Liposome Dermatics: Assessment of Long-Term Stabilitywever, seems to be rather unknown. A peek into the literature leads to the belief that liposomes must be very stable because hardly anybody speaks about their stability problems. However, everybody knows that the stability of dosage forms is a real problem of drug safety. In the first part of this c
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