Titlebook: Lipoprotein(a); Karam Kostner,Gerhard M. Kostner,Peter P. Toth Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive

fringe

Contemporary Aspects of Lp(a) Metabolism and Therapies Based on Tracer Kinetic Studies in Humans,ble isotope tracers and compartmental modelling has provided deeper understanding of the physiology and pathophysiology of Lp(a) metabolism in humans, and the mode of action of lipid-regulating agents. Kinetic data have demonstrated that newly synthesized Lp(a)-apolipoprotein (apo) B-100 and Lp(a)-a

债务

Role of Proprotein Convertase Subtilisin Kexin Type 9 in Lipoprotein(a) Metabolism, inhibitory action on LDL receptor (LDLR) expression. As a result, PCSK9 inhibitors lower the circulating concentrations of LDL. Surprisingly, these therapeutic agents also reduce the plasma levels of another class of atherogenic lipoproteins, lipoprotein(a) [Lp(a)]. This observation has driven rese

neutrophils

The Role of Cell Surface Receptors in Lp(a) Catabolism,a) is defined by the large apolipoprotein(a) [apo(a)] glycoprotein which is polymorphic in size and is synthesised in the liver before addition to LDL. The main clearance route for Lp(a) is via the liver with some role for the kidneys. Unlike LDL, there is no clear pathway of catabolism for Lp(a). B

不自然

Physiological Roles and Functions of Lipoprotein(a),y enigmatic lipoprotein whose range of physiologic functions is as yet incompletely described. Structurally, it is a low-density lipoprotein particle that is covalently bound with the glycoprotein apoprotein(a) via noncovalent interactions as well as a disulfide linkage to apoprotein B100. Apoprotei