Titlebook: Lipids and Skin Health; Apostolos Pappas Book 2015 Springer Science+Business Media New York 2015 Acne.Dermatitis.Dermatology.Epidermis.Lip

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Book 2015f our body, the skin.  The book covers the fundamental biology of the skin, and the major involvement of the transcriptional factors that govern lipid synthesis and the bioactive lipids in this intriguing organ. All layers of skin are presented, as well as their relevant lipids from the epidermis to

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th.Provides a clear understanding of skin lipids, allowing f.Lipids and Skin Health is the first effort to summarize and review the studies, ideas, and research that link lipid metabolism to the largest organ of our body, the skin.  The book covers the fundamental biology of the skin, and the major

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Skin Lipids: An Introduction and Their Importancet time. Although the very first baby steps of lipids and skin together took place about 50 years ago in the laboratories of skin lipid pioneer scientists such as professors Downing, Strauss, and Nicolaides, nowadays it seems that together they could rapidly turn into one of the most emerging and int

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Skin Barrier, Structure, and Propertieser land-living higher vertebrates, this barrier is constituted by a uniquely organized lipid material situated between the cells of the horny layer of skin. Not having a native reference for the molecular organization of the horny layer’s lipid material has until recently limited our fundamental und

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Polyunsaturated Fatty Acid Oxygenated Metabolites in Skinributing to cellular development and communications, in particular through the production of oxygenated metabolites. These potent mediators are formed through enzymatic or free radical-mediated reactions and include the eicosanoids, octadecanoids, docosanoids and a number of related lipid species. T

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Skin Ceramidesere is a loss of phospholipids and accumulation of a different polar lipid. In 1965, Nicolaides identified this neutral polar stratum skin lipid class as ceramide. This finding was based on infrared spectral data and was added as a footnote to the proof of the manuscript (personal communication). Lo

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Chapter 6 Cholesterol Metabolism in the Epidermised to form membranes in cells and is also crucial for the formation of the extracellular lamellae in the stratum corneum that provides the permeability barrier for the skin. Keratinocytes in the epidermis, as they stratify and differentiate, synthesize a variety of structural proteins (primarily ker

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Nuclear Hormone Receptors and Epidermal Differentiationd physical and environmental challenges. Among the numerous cells present in the skin epidermis, keratinocytes are the predominant cell type and are also the major contributor to the protective functions of this organ. Keratinocytes undergo an elaborate terminal differentiation process to form a con

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The Brain of the Skin: Sebaceous Glandy neuropeptide program are of major importance. Sebocytes express bioactive receptors for peptide hormones, including neurotransmitters, which are mostly arranged on the cell surface (CRHR, MCR, µ-opiate receptors, VPAC receptors, CBR, histamine 1 receptor, IGF-1 receptor, EGFR, and GHR), and for st