书目名称 | Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications | 编辑 | A. S. H. Ong,L. Packer | 视频video | | 丛书名称 | Molecular and Cell Biology Updates | 图书封面 |  | 描述 | Antioxidants inhibit the formation and spread of free radicals which can be damaging in biological systems. Free radicals form in biological systems through metabolism, but it is also realized that exogenous environmental sources, such as radiation, food, and drugs, contribute significantly to the generation of free radicals in biological systems. Being reactive species, free radicals are short-lived and do not travel far from cellular targets. Their concentration in biological systems is very low and is difficult to detect directly by electron spin resonance spectroscopy (ESR). Indirect methods of reactions of radicals with specific biomolecules are also sufficiently sensitive to detect quantitatively their presence. Thus the response of antioxidant defenses which react with radical species, can serve as an indirect measure that free radicals have been formed. Redox-based antioxidants change their oxidation state and antioxidants become free radicals themselves. Often, however, the antioxidants give rise to more persistent free radicals, sometimes owing to delocalization of the lone electron around ring structures (in vitamin E, ubiquinones, and certain carotenes). Persistent free | 出版日期 | Book 1992 | 关键词 | biochemistry; biomolecules; membrane; metabolism; spectroscopy | 版次 | 1 | doi | https://doi.org/10.1007/978-3-0348-7432-8 | isbn_softcover | 978-3-0348-7434-2 | isbn_ebook | 978-3-0348-7432-8 | copyright | Springer Basel AG 1992 |
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