Titlebook: Lipid metabolism in the normoxic and ischaemic heart; H. Stam,G. J. Vusse Conference proceedings 1987 Springer-Verlag Berlin Heidelberg 19

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Substrates for energy metabolism in the heart: the role of the interstitial compartmentise to O.-., may be involved in the damage of the ischaemic heart. The significance of the interstitium in ischaemia and in fibrosis following long standing cardiac lipidosis is briefly discussed, as well as the possible mechanisms involved in fatty acid transport in the heart.

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The role of the carnitine system in myocardial fatty acid oxidation: carnitine deficiency, failing mte of isolated muscle mitochondria. In some of these patients we detected medium-chain acyl-CoA dehydrogenase deficiency..Patients with primary carnitine deficiency caused by a renal carnitine leak often show cardiomyopathy, which completely disappears under carnitine therapy. Cardiomyopathy may als

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Phospholipases of the myocardiumes were stimulated by calcium, suggesting that they are different from calcium-independent phospholipases C found in liver and brain. The pathophysiological significance of these four cytosolic forms of phospholipase C remains to be determined. Thus, under injury-promoting conditions, phospholipase

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