Titlebook: Lipid Signaling in Human Diseases; Julian Gomez-Cambronero,Michael A. Frohman Book 2020 Springer Nature Switzerland AG 2020 Lipid signalin

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Role of Phospholipase D-Derived Phosphatidic Acid in Regulated Exocytosis and Neurological Diseaseacellular or extracellular entities. Accordingly, it has been known for decades that lipids, especially those coming from diet, are important to maintain normal physiological functions and good health. On the other side, the exact molecular nature of these beneficial or deleterious lipids, as well a

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Functions of Nuclear Polyphosphoinositidessease, the PtdIns have another less well-known site of action in the cell nucleus..Recent studies show that PtdIns use a variety of strategies to alter DNA responses. Here, we provide an overview of these newly identified forms of gene expression control, which should be considered when studying the

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Platelet-Activating Factor as an Effector for Environmental StressorsThe goal of this chapter is to present evidence that the potent lipid mediator platelet-activating factor (PAF) is involved in the effects of many stressors ranging from cigarette smoke to ultraviolet B radiation. These environmental stressors can generate PAF enzymatically as well as PAF-like lipid

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conservative

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Inositide-Dependent Nuclear Signalling in Health and Diseaseand disease. Emerging evidence shows that alterations in multiple inositide signalling pathways are involved in pathophysiology, not only in cancer but also in other diseases. Here, we give an overview of the main features of inositides in the cell, and we discuss their potential as new molecular th

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