| 书目名称 | Lipase and Phospholipase Protocols | | 编辑 | Mark Doolittle,Karen Reue | | 视频video | | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | The lipases and phospholipases represent a diverse group of enzymes that are expressed in animals, plants, fungi, and bacteria. Their ubiquitous distribution among all species is a testament to the essential roles played by these enzymes in lipid storage, mobilization and metabolism, membrane homeostasis and remodeling, endocrine and immune functions, and signal tra- duction. In humans, lipases and phospholipases are also thought to contribute to complex diseases, such as atherosclerosis, obesity, arthritis, and cancer, as well as to single gene defects, such as Wolman‘s disease and Type I hyperlipoproteinemia. Enzymatically, the lipases are unique, since they hydrolyze substrates that are either insoluble, or only partly soluble, in aq- ous solvents; thus, enzyme catalysis takes place at a lipid-water interface. The interface comprises at least two, and often more, discrete bulk and s- face phases, in which the enzyme, substrate, and products oflipolysis disperse among these phases based on their physical properties. Furthermore, the d- tribution of these components changes continuously as lipolysis proceeds. Thus, the lipases and phospholipases are fundamentally different from an | | 出版日期 | Book 1999 | | 版次 | 1 | | doi | https://doi.org/10.1385/1592595812 | | isbn_softcover | 978-1-61737-069-4 | | isbn_ebook | 978-1-59259-581-5Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 1999 |
The information of publication is updating
|
|
发表于 2025-3-21 20:04:08
