Titlebook: Life-Threatening Coagulation Disorders in Critical Care Medicine; Viola Hach-Wunderle,Peter P. Nawroth Book 1997 Springer-Verlag Berlin He

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state replaces another in the responsibility for its international relations. However, such a replacement may be the result of a gradual process rather than an instantaneous switch, which creates the risk that the law of state succession may incorrectly appraise realities on the ground and therefor

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Pathophysiology, Presentation, and Treatment of Conditions Associated with DICg disorders that can trigger DIC. Its clinical manifestations are diverse, its diagnostic criteria have not been uniformly defined, and various therapeutic strategies, some still experimental, have been advocated for patient use. Since morbidity and survival depend mainly on the specific cause of th

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Consumption Coagulopathy: Principles of Management inhibitors, and platelets. Increased procoagulant activity and platelet activation tend to exhaust the procoagulant potential, leading to an increasing bleeding diathesis. Disseminated fibrin deposition in the microvasculature of the lungs, liver, heart, and kidneys, reactive hyperfibrinolysis, and

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Acquired Inhibitors Against Factor VIII and Factor IXwith equal frequency in men and women and are most common in the ranges of 20–30 and 60–80 years of age. The hemorrhagic diathesis is usually manifested by cutaneous and muscular bleeding, intra- and postoperative bleeding, and intraabdominal hemorrhage. Hemarthrosis is far less common than in patie

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Lupus Anticoagulantses. The presence of lupus anticoagulants can predispose to thrombosis and recurrent abortion. Both arterial and venous thrombosis have been described. Reduced anticoagulant activity of activated protein C has been discussed as a possible pathophysiologic mechanism. Various functional and immunologic

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Bleeding in Transplantation Surgeryunderlying organ defect. Thus, in the absence of secondary organ damage, the risk of bleeding in cardiac transplantation is basically the same as in coronary bypass surgery. The hemostatic defect that occurs as a result of decompensated heart failure with consequent multiple organ failure, sometimes