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Titlebook: Leukocyte Typing II; Volume 3 Human Myelo Ellis L. Reinherz,Lee M. Nadler,Irwin D. Bernstein Conference proceedings 1986 Springer-Verlag Ne

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Glycolipid Specificities of Anti-Hematopoietic Cell Antibodies,epresent developmentally arrested populations of hematopoietic cells (1,2). The reasons why changes in cell surface carbohydrate expression accompany differentiation and distinguish mature hematopoietic subsets are obscure, although several roles for oligosaccharides of cell surface glycoconjugates
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Antibodies Specific for the Mac-1, LFA-1, p150,95 Glycoproteins or Their Family, or for Other Granund mice (1,2). These glycoproteins, the lymphocyte function- associated 1 (LFA-1), macrophage 1 (Mac-1), and p150,95 molecules each contain a different α subunit noncovalently associated with the common . subunit in an α... structure. Monoclonal antibodies specific for the LFA-1 and Mac-1 molecules
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Functional Studies with Monoclonal Antibodies Against Function-Associated Leukocyte Antigens, human counterpart to murine LFA-1 have subsequently been produced in several laboratories (3–6). Anti-LFA-1 mAbs inhibit a variety of T cell functions including cytotoxic T cell (CTL) activity (1–6), natural killer (NK) cell activity (3–6), killer (K) cell activity (6), T cell-dependent immunoglobu
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Serological, Immunochemical, and Functional Analysis of the Heterogeneity of the Workshop Monoclonay to block T cell-mediated cytotoxicity in the absence of complement. The cell surface molecule recognized by these antibodies is expressed on a variety of hematopoietic cells and consists of a heterodimer with subunits of 90 and 160 Kd (1). This molecule is one of a family of structurally related m
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Monoclonal Antibodies That Identify Mo1 and LFA-1, Two Human Leukocyte Membrane Glycoproteins: A Reonal reagents have been used as specific probes for the identification and characterization (functional and structural) of plasma membrane receptors that participate in antigen recognition, proliferation, and target cell cytotoxicity (1–3). Likewise, in the myeloid lineage, other monoclonal antibodi
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Murine Monoclonal Anti-P,od group ABH, Le, MN system (1). Because of their strength, purity, and uniform quality they are excellent tools for serological studies as well as for more basic hematological and biochemical studies on blood group antigens.
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NK-Associated and LFA-1 Antigens: Phenotypic and Functional Studies Utilizing Human NK Clones,ruction of virally transformed cells and tumor cells (see Ref. 1 for review), control of hematopoietic differentiation (2), and regulation of immunoglobulin production by B lymphocytes (3). Although the precise role of NK active lymphocytes in the majority of these experiments remains to be clarifie
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Reactivity Patterns of Monoclonal Antibodies Against Myeloid-Associated Antigens with Human Natural identified as large lymphocytes with an abundant cytoplasm, an indented nucleus, and azurophilic granules (“large granular lymphocytes,” LGL) (2). Although the origin and function of NK cells is still a matter of some controversy, it has been postulated that these cells play an important role in th
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