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Titlebook: Leukemia; Report of the Dahlem I. L. Weissman Conference proceedings 1985 Dr. S. Bernhard, Dahlem Konferenzen, Berlin 1985 cell.evolution.g

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书目名称Leukemia
副标题Report of the Dahlem
编辑I. L. Weissman
视频video
丛书名称Dahlem Workshop Report
图书封面Titlebook: Leukemia; Report of the Dahlem I. L. Weissman Conference proceedings 1985 Dr. S. Bernhard, Dahlem Konferenzen, Berlin 1985 cell.evolution.g
描述and how the known vertebrate homologues of these genes are expressed normally in differentiation and proliferation pathways as well as abnormal­ ly in well-defined lymphomagenic and other oncogenic pathways. What emerged from this meeting are a better understanding of the evolution of these gene systems themselves and an elucidation of simpler systems open to more rapid genetic and molecular genetic analysis to reveal the normal functions of these genes and their gene products. Thus we sought new answers to several old questions concerning differenti­ ation, proliferation, and neoplastic transformation. We gathered together in an unusual format - that of the unique Dahlem Workshops - not just to reiterate data which has recently emerged but to think about how these findings might lead to new approaches for the understanding and therapy of the leukemias and lymphomas. We deliberately chose experts from several different disciplines, ranging from the clinicians who diag­ nose, describe, and treat these maladies, to the molecular geneticists trying to reduce the analysis of the problem to its simplest variables in the simplest systems possible.
出版日期Conference proceedings 1985
关键词cell; evolution; gene; genes; lead; leukemia; lymphocytes; lymphoma; oncogene; proliferation; therapy; tumor
版次1
doihttps://doi.org/10.1007/978-3-642-69722-7
isbn_softcover978-3-642-69724-1
isbn_ebook978-3-642-69722-7
copyrightDr. S. Bernhard, Dahlem Konferenzen, Berlin 1985
The information of publication is updating

书目名称Leukemia影响因子(影响力)




书目名称Leukemia影响因子(影响力)学科排名




书目名称Leukemia网络公开度




书目名称Leukemia网络公开度学科排名




书目名称Leukemia被引频次




书目名称Leukemia被引频次学科排名




书目名称Leukemia年度引用




书目名称Leukemia年度引用学科排名




书目名称Leukemia读者反馈




书目名称Leukemia读者反馈学科排名




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Specificity of Hemopoietic Growth Factors,stinguish between these are difficult but feasible. Finally, strong requirements in culture, even of lineage-specific nature, do not necessarily imply regulatory roles for the factors concerned in the whole animal. Such roles remain to be demonstrated for most of the factors considered.
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The Receptor-mediated Leukemogenesis Hypothesis: A Model of Retroviral Oncogenesis by Viral Stimulato assume that malignant cells utilize normal mitogenic pathways for their sustained proliferation, and that one must look to means by which a particular class of cells controls its proliferation if one wishes to understand how malignancy develops in that cell type.
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Conference proceedings 1985 well-defined lymphomagenic and other oncogenic pathways. What emerged from this meeting are a better understanding of the evolution of these gene systems themselves and an elucidation of simpler systems open to more rapid genetic and molecular genetic analysis to reveal the normal functions of thes
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Induction of B Cell Proliferation and Differentiation, “T cell replacing factors.” Efforts to purify the various factors, to understand their mode of action, and to isolate their receptors will be a major theme of research on B cells during the next several years.
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Regulation of Hematopoietic Differentiation and Its Disruption Group Report,dditional item of discussion was possible therapeutic strategies based on these differentiation pathways. In order to address this theme, the group considered in detail several basic questions concerning normal pathways of hematopoietic growth and differentiation.
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