| 书目名称 | Leucocyte Trafficking |
| 副标题 | The Role of Fucosylt |
| 编辑 | Alf Hamann,Khusru Asadullah,Arndt Schottelius |
| 视频video | |
| 概述 | Includes supplementary material: |
| 丛书名称 | Ernst Schering Foundation Symposium Proceedings |
| 图书封面 |  |
| 描述 | .An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.. |
| 出版日期 | Conference proceedings 2004 |
| 关键词 | Chemokine; Glycotransferases; Leukocyte trafficking; Migration; Selectins; Skin inflammation; T cells; endo |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-662-05397-3 |
| isbn_softcover | 978-3-662-05399-7 |
| isbn_ebook | 978-3-662-05397-3Series ISSN 0947-6075 |
| issn_series | 0947-6075 |
| copyright | Springer-Verlag Berlin Heidelberg 2004 |
发表于 2025-3-21 19:18:20
