Titlebook: Lessons on Caffeine, Cannabis & Co; Plant-derived Drugs Angelika Böttger,Ute Vothknecht,Alexander Wolf Textbook 2018 Springer Nature Switz

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GPCRs as Targets for Plant-Derived Drugse receptors, cannabinoid receptors, dopamine- and serotonin (5HT) receptors/transporters and opiate receptors. They are targets for compounds such as cannabis, muscarine and atropine, caffeine, cocaine, morphine and hallucinogenic drugs, among others.

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Textbook 2018mans. It explains the biosynthesis and molecular action of nicotine, cannabis, caffeine and Co, describes the effects of these drugs on signal transduction at receptors and ion channels in animals, their relevance for human health and their potential for recreational use and abuse. It also offers a

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Ion Channelsmembrane potential is maintained and explain the molecular architecture and function of several ion channels. As an example, we elucidate, how voltage- and ligand-gated ion channels work together at the neuromuscular junction and at synapses. Finally, we briefly introduce the large family of “transient receptor potential” (TRP) ion channels.

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Historical and Current Perspectivegens or painkillers, even though this often requires careful adjustment of the dose to avoid toxic effects. Last but not the least, since the onset of modern science and technical development, plant secondary metabolites and their derivatives have been exploited for technical applications.

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Terpenes and Terpenoidshway. Tailoring enzymes leads to the variations observed. End products are important for plant growth such as hormones (gibberellin and brassinosteroids) or carotenoids. They can be simpler structures, which are sometimes also volatile (such as menthol or ß-caryophyllene) or more complex, even polycyclic (such as ryanodine or stigmasterol).

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