书目名称 | Leptin | 编辑 | V. Daniel Castracane (Professor Emeritus and Direc | 视频video | | 概述 | The timing of this volume is long overdue and it will be the first comprehensive coverage of leptin physiology in the field.Includes supplementary material: | 丛书名称 | Endocrine Updates | 图书封面 |  | 描述 | The discovery of leptin by Friedman and his colleagues in 1994 was a seminal discovery in the study of metabolism, providing a new tool to study energy expenditure and appetite regulation. Early studies actively investigated many aspects of metabolism, obesity, and diabetes but it was soon evident that leptin was much more than a metabolic hormone. Today leptin, with almost 11,000 reports in the world‘s literature, is recognized to be important in many areas of physiology with strong suggestions for involvement in clinical conditions as well. Leptin, of course, remains of great interest in obesity and diabetes but other, previously unimagined, areas are now in the realm of leptin physiology. Perhaps leptin and its involvement in many areas of reproductive physiology may be of greatest interest outside of obesity, but other physiological arenas are becoming increasingly involved in the broader understanding of leptin and its pleiotropic functions. These areas include cardiovascular disease, bone physiology, immune regulation, and even cancer and genetics. Clinical trials have suggested other areas of leptin pharmaceutical potential beyond the original promise of obesity management. | 出版日期 | Book 2007 | 关键词 | bone; hormone; leptin receptors; metabolism; neuroendocrinology; obesity; physiology; protein; reproduction | 版次 | 1 | doi | https://doi.org/10.1007/978-0-387-31416-7 | isbn_softcover | 978-1-4419-4065-0 | isbn_ebook | 978-0-387-31416-7Series ISSN 1566-0729 | issn_series | 1566-0729 | copyright | Springer-Verlag US 2007 |
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