Titlebook: Leishmania; Methods and Protocol Joachim Clos Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 Neglected Tropic

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Vertebra

Quantification of , Parasites in Murine Models of Visceral Infection,odels of visceral infection lack the clinicopathological aspects of VL in humans, they have been proven useful at advancing our knowledge in the . field. Indeed, these models have been used not only to better understand the pathophysiology of the infection but also in drug and vaccine development. T

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,Syrian Hamster as an Advanced Experimental Model for Visceral ,s with . species causing visceral leishmaniasis (VL) closely mimic the disease in the natural hosts, including target organs, lesions, and clinical course. Therefore, despite some shortcomings (e.g., genetic background, price, and scarcity of reagents), it is probably the best laboratory rodent mode

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Experimental Cutaneous ,: Mouse Models for Resolution of Inflammation Versus Chronicity of Disease,parasite control and resolution of inflammation as well as of parasite evasion and chronicity of disease. In addition, over many years .infected mice have been successfully used to analyze the function of newly discovered immune cell types, transcription factors, cytokines, and effector mechanisms i

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