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Titlebook: Lebensqualität im Alter; Perspektiven für Men Sandra Verena Müller,Claudia Gärtner Book 2016 Springer Fachmedien Wiesbaden 2016 Chronische

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Christian Wolff,Uwe Gövert,Bettina Kuske,Sandra Verena Müllerf immune cancer evasion has enabled the development of new cancer immunotherapy targeted to inhibitory immune checkpoints: PD-1, PD-L1 and CTLA4. Dramatic results were obtained in advanced melanoma (34% survival at 5 years with anti-PD-1) and non-small cell lung cancer, and proof of efficacy has bee
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Christian Wolff,Uwe Gövert,Bettina Kuske,Sandra Verena Müllerf autoimmune, degenerative, or allergic character. Rheumatoid arthritis (RA) is by definition a chronic disease with an autoimmune inflammatory attack on diarthrodial cartilaginous joints. The development of new treatment neutralizing cytokines involved in the inflammatory attack has given relief an
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Antonia Coppus,Hildegard Telbis-Kankainenf autoimmune, degenerative, or allergic character. Rheumatoid arthritis (RA) is by definition a chronic disease with an autoimmune inflammatory attack on diarthrodial cartilaginous joints. The development of new treatment neutralizing cytokines involved in the inflammatory attack has given relief an
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Bettina Kuske,Uwe Gövert,Christian Wolff,Sandra Verena Müllern antigens are in general hardly processed by MHC class I pathway, combination with suitable antigen delivery systems and/or adjuvants is required for efficient CD8+ and CD4+ T-cell inductions for the clinical development of protein vaccine. Several protein vaccine types have been studied for their
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Matthew P. Janicki protein is highly immunogenic, which indicates that WT1 should be a promising target antigen for cancer immunotherapy. The identification of human WT1 cytotoxic T lymphocyte (CTL) epitopes and the demonstration using a mouse model that WT1 could serve in vivo as a target antigen for cancer immunoth
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Ludger Kolhoff exert potent cytotoxicity against a variety of cancer cells irrespective of MHC class I expression, and bridge innate and adaptive immunity. They comprise 1–5 % of peripheral blood mononuclear cell (PBMC); the majority of them express the Vγ9Vδ2 T cell receptor that recognizes phosphoantigens. Ther
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