Titlebook: Learning-Through-Touring; Juliet Sprake Book 2012 SensePublishers 2012 Educational Technology

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ago that is was first shown that some transformed mast cell lines could secrete these proteins. Since then we have come to understand that normal mast cells and basophils, the cells that we most commonly associate with the FcεRI and IgE-dependent responses, may also secrete a wide array of cytokines

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Juliet Sprakeh symptoms and signs of acute pancreatitis. Elevated serum IgG4 concentrations are noted in a high proportion of cases, and the pancreas characteristically shows a marked lymphoplasmacytic infiltrate with IgG4-positive plasma cells and fibrosis. This entity has been termed lymphoplasmacytic sclerosi

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tion, and tissue infiltration by IgG4-positive plasma cells. The exact etiology of IgG4-related disease remains unclear with no known role of the IgG4 molecule itself being identified. Although the pancreas and salivary glands are the main organs affected, the involvement of other organs has also be

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