Titlebook: Leading Pharmaceutical Innovation; Trends and Drivers f Oliver Gassmann,Gerrit Reepmeyer,Maximilian Zedtwi Book 20082nd edition Springer-Ve

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The Science and Technology Challenge: How to Find New Drugs,and technologies. While innovation activities of established pharmaceutical companies were traditionally based on organic chemistry, biochemistry and chemical engineering, biotechnology companies have built a reputation in many novel areas, such as cell biology, molecular genetics, protein chemistry and encymology (Whittaker and Bower 1994).

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Book 20082nd editioninvestigates and highlights a set of proactive strategies aimed at generating sustainable competitive advantage based on value-generating business practices. We focus on three sources of pharmaceutical innovation: new management methods in the drug development pipeline, new technologies as enablers

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The Pipeline Management Challenge: How to Organize Innovation,ceutical companies are required to deliver between two and four new drugs every year in order to maintain or exceed the double-digit growth expectations. Given the high attrition rates in drug development, they have to fill the R&D pipeline with as many new drug candidates as possible.

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Management Answers to Pharmaceutical R&D Challenges,up in 2002, and Basilea Pharmaceutica. This is a further source of promising compounds for the company’s product pipeline. Including several research related agreements with other companies, Roche ranks among the industry leaders in terms of licensing. In total, the Roche Group owns 166 patents (Reuters 2002).

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The Pipeline Management Challenge: How to Organize Innovation, of pharmaceutical and biotechnology companies target the therapeutic area of oncology which covers all types of cancer related diseases. Cardiovascular, central nervous system and respiratory related diseases are other important therapy areas. Depending on the size of their current business, pharma

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The Internationalization Challenge: Where to Get Access to Innovation,ountries, where high R&D costs can only be recouped by selling the resulting drug to a worldwide market. International trade statistics by the WTO (2002) illustrate the tremendous increase in international business over the past twenty years. For instance, the amount of worldwide merchandise exports

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Management Answers to Pharmaceutical R&D Challenges,l in-house research organization, the pharmaceuticals division’s R&D network also includes Genentech and Chugai, which function as largely independent research satellites. In addition, Roche has opt-in rights to the programs of external development organizations it has created, such as BioXell, set