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Titlebook: CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues; Philip Rubin (Professor Emeritus, Chair Emeritus), Book 2008 Springer-V

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书目名称CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues
编辑Philip Rubin (Professor Emeritus, Chair Emeritus),
视频videohttp://file.papertrans.cn/582/581766/581766.mp4
概述This volume is based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006.Written by experts in the field, it addresses a number of critical topics relating to
丛书名称Medical Radiology
图书封面Titlebook: CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues;  Philip Rubin (Professor Emeritus, Chair Emeritus), Book 2008 Springer-V
描述The rapid advances in radiation oncology, radiation biology, and radiation therapy physics have led to an accumulation of information on the interactions of radiation with other therapeutic modalities, such as the wide array of chemotherapeutic agents being employed in combination with radiation therapy, as well as the multiple biologic response modi? ers that are being used in combination with radiation therapy. It is now recognized that they have a signi? cant impact on normal tissue toxicities. The radiation doses customarily deemed safe on the basis of past experience have now, when combined with other modalities, led to severe late effects in different vital organs. The previously de? ned radiation tolerance dosages remain as valuable guides, but their applicability has changed signi? cantly. The emphasis is now placed on the volume of the organ irradiated, as well as the dose being used. New constructs rel- ing global (whole organ) and focal (partial volume) injury as a function of the dose volume histogram emerge as a signi? cant predictor of late effects on normal tissues. There are now mathematical models such as the model on standard dose, time–dose factors, and accumulat
出版日期Book 2008
关键词Fatigue; TNM; TNM staging system; cancer; cancer treatment; cell; imaging; inflammation; pathology; physiolog
版次1
doihttps://doi.org/10.1007/978-3-540-49070-8
isbn_softcover978-3-642-08032-6
isbn_ebook978-3-540-49070-8Series ISSN 0942-5373 Series E-ISSN 2197-4187
issn_series 0942-5373
copyrightSpringer-Verlag Berlin Heidelberg 2008
The information of publication is updating

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Philip Rubin (Professor Emeritus, Chair Emeritus),This volume is based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006.Written by experts in the field, it addresses a number of critical topics relating to
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Medical Radiologyhttp://image.papertrans.cn/l/image/581766.jpg
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Ionizing Radiation and the Endothelium,l or sublethal injury to EC. The latter may alter considerably the complex physiology of the endothelium. Some functions are inhibited or abolished: fibrinolysis, synthesis of various enzymes and cytokines, attachment of EC to the basal lamina, angiogenesis, etc.
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Cancer-Related Fatigue as a Late Effect:,ive survey conducted in part to characterize CRF severity in relation to depression and shortness of breath and to compare symptom severity in radiation and chemotherapy patients and over time. Careful characterization of CRF will aid in the development of effective methods to manage this disabling symptom.
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CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues
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