书目名称 | Lassa Fever: Epidemiology, Immunology, Diagnostics, and Therapeutics | 编辑 | Robert Garry | 视频video | http://file.papertrans.cn/582/581737/581737.mp4 | 概述 | Provides detailed information on genetics, function and epidemiology of LASV.Reviews key findings from 50 years of Lassa fever research.Explores latest diagnostic strategies as well as antibody therap | 丛书名称 | Current Topics in Microbiology and Immunology | 图书封面 |  | 描述 | This volume provides a comprehensive and up-to-date overview of the various aspects of Lassa virus (LASV), the causative agent of Lassa fever, a frequently fatal zoonotic disease endemic to West Africa. Compiled by world-leading experts in the field, this book provides an introduction to the 50-year history of Lassa fever research, the genetic diversity of LASV, and its geographic distribution. Subsequent chapters focus on the ecology and epidemiology of LASV, discussing in-depth the interactions of the virus with its hosts - multimammate mice and other rodents - and the interactions between these animal reservoirs and humans. The book also details the many advances in understanding the structural biology and replication of LASV, including new insights into the structure and function of its proteins. These advances in the basic understanding of LASV biology have enabled the development of LASV countermeasures, including sensitive and specific diagnostic assays. Promising drugcandidates, including monoclonal antibodies, and vaccines are also discussed. A final and essential chapter addresses current and future clinical practice for clinical management of Lassa fever. .This volume is | 出版日期 | Book 2023 | 关键词 | viral hemorrhagic fever; healthcare infrastructure; rodent control; contact tracing; Kenema Government H | 版次 | 1 | doi | https://doi.org/10.1007/978-3-031-35807-4 | isbn_softcover | 978-3-031-35809-8 | isbn_ebook | 978-3-031-35807-4Series ISSN 0070-217X Series E-ISSN 2196-9965 | issn_series | 0070-217X | copyright | Springer Nature Switzerland AG 2023 |
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