书目名称 | Label-Free Monitoring of Cells in vitro |
编辑 | Joachim Wegener |
视频video | |
概述 | Overview chapters introduce the newcomer to the topic covered.Series covers hot topics of frontier research summarized by reputed scientists in the field.Volumes are useful and of relevance for a long |
丛书名称 | Bioanalytical Reviews |
图书封面 |  |
描述 | .This book is dedicated to label-free, non-invasive monitoring of cell-based assays and it comprises the most widely applied techniques. Each approach is described and critically evaluated by an expert in the field such that researchers get an overview on what is possible and where the limitations are. The book provides the theoretical basis for each technique as well as the most successful and exciting applications..Label-free bioanalytical techniques have been known for a long time as valuable tools to monitor adsorption processes at the solid-liquid interface in general – and biomolecular interaction analysis (BIA) in particular. The underlying concepts have been progressively transferred to the analysis of cell-based assays. The strength of these approaches is implicitly given with the name ‘label-free‘: the readout is independent of any label, reagent or additive that contaminates the system under study and potentially affects its properties. Thus, label-free techniques provide an unbiased analytical perspective in the sense that the sample is not manipulated by additives but pure. They are commonly based on physical principles and read changes in integral physical properties |
出版日期 | Book 2019 |
关键词 | label-free monitoring; cell-based assays; surface plasmon resonance; resonance waveguides; impedance ana |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-030-32433-9 |
isbn_softcover | 978-3-030-32435-3 |
isbn_ebook | 978-3-030-32433-9Series ISSN 1867-2086 Series E-ISSN 1867-2094 |
issn_series | 1867-2086 |
copyright | Springer Nature Switzerland AG 2019 |