Titlebook: Label-Free Monitoring of Cells in vitro; Joachim Wegener Book 2019 Springer Nature Switzerland AG 2019 label-free monitoring.cell-based as

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Y. Fangosylation of ceramide is unique in that it takes place at the lumen of the endoplasmic reticulum (ER) while all the other glycosylation reactions of GSLs occur at the Golgi apparatus and that the reaction product, galactosylceramide (GalCer), is only used for the synthesis of the gala series GSLs in

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Immunization

of several proteins. Protein .-linked fucosylation is unusual glycosylation associated with important biological functions such as Notch signaling. Two distinct fucosylation pathways synthesizing .-fucosylglycans have been reported on cysteine-knotted core proteins, namely, epidermal growth factor-l

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Label-Free Monitoring of 3D Tissue Models via Electrical Impedance Spectroscopy,he latter have been used with increasing success throughout the last decades even though their limitations were well-known. Two-dimensional cell layers cannot fully mimic the complex architecture of real tissue mainly because cell-cell interactions, cell communication, cell signaling, extracellular

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On the Use of the Quartz Crystal Microbalance for Whole-Cell-Based Biosensing, such is simple. For screening purposes, one can easily run numerous resonators in parallel. The main problem is the interpretation of experimental data. Living cells by their very nature are enormously complicated and the limited amount of information obtained from a QCM experiment therefore is not

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Microphysiometry,s in cellular disease models. Following a brief review of recent developments in the field, this contribution presents the most important branches of current sensor-based methods of microphysiometry. The primary parameters assessed by microphysiometry are extracellular pH changes and the concentrati

Lyme-disease

Optical Waveguide-Based Cellular Assays,ications in monitoring cell phenotypic responses in native cells mostly due to its adoption to microtiter plates, the de facto footprint for drug discovery. This chapter first reviews RWG biosensor configurations and reader systems, followed by a discussion about how to apply them to facilitate drug